Inhoudsopgave
Is allopurinol gevaarlijk?
Bijwerkingen in het begin: misselijkheid en braken. U heeft hier minder last van als u allopurinol tijdens of vlak na het eten inneemt, of met wat voedsel. Verder huiduitslag en overgevoeligheid. Waarschuw direct een arts bij benauwdheid, blaren op de huid en slijmvliezen of zwelling in het gezicht.
Welke dosis allopurinol?
De begindosering is laag, bijvoorbeeld 100 mg per dag, om de kans op bijwerkingen te verkleinen. De meest gebruikelijke dosering voor een volwassene is 300 mg per dag. Over het algemeen varieert de dosering van 100 mg per dag (=24 uur) bij lichte, tot 900 mg per dag bij ernstige gevallen.
What is allopurinol and how should it be used?
Allopurinol is used to prevent gout attacks, not to treat them once they occur. How should this medicine be used? Allopurinol comes as a tablet to take by mouth. It is usually taken once or twice a day, preferably after a meal. To help you remember to take allopurinol, take it around the same time every day.
When should I stop taking allopurinol for gout?
Discontinue allopurinol at the first appearance of a skin rash, painful urination, blood in the urine, eye irritation, or facial swelling and seek urgent medical advice. Allopurinol is a maintenance treatment for gout or high uric acid levels so should be taken regularly even once a gout attack has resolved.
How long does it take for allopurinol to be metabolized?
Allopurinol is almost completely metabolized to oxipurinol within two hours of oral administration, whereas oxipurinol is slowly excreted by the kidneys over 18–30 hours. For this reason, oxipurinol is believed responsible for the majority of allopurinol’s effect.
How much water should I drink while taking allopurinol?
Drink at least eight glasses of water or other fluids each day while taking allopurinol unless directed to do otherwise by your doctor. What should I do if I forget a dose? Take the missed dose as soon as you remember it.