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What is another name for the sonic hedgehog gene?
Both the gene and the protein may also be found notated alternatively as “Shh”. Sonic hedgehog is one of three proteins in the mammalian signaling pathway family called hedgehog, the others being desert hedgehog (DHH) and Indian hedgehog (IHH). SHH is the best studied ligand of the hedgehog signaling pathway.
What is the function of Sonic hedgehog protein?
Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. This protein is important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body.
What is the role of the sonic hedgehog in the CNS?
Patterning of the central nervous system. The sonic hedgehog (SHH) signaling molecule assumes various roles in patterning the central nervous system (CNS) during vertebrate development. One of the most characterized functions of SHH is its role in the induction of the floor plate and diverse ventral cell types within the neural tube.
Who are the characters in Sonic the Hedgehog games?
A variety of Sonic characters gathered. Clockwise from top: Doctor Eggman, Rouge the Bat, Shadow the Hedgehog, Knuckles the Echidna, Sonic the Hedgehog, Amy Rose, Miles “Tails” Prower, Cream the Rabbit, a Chao, and Blaze the Cat. Art by Yuji Uekawa.
https://www.youtube.com/watch?v=KM1nyU1kJa0
When did Sonic the Hedgehog come out?
Debuting on June 23, 1991 (also Sonic’s birthday), SEGA released the first game in the series, Sonic the Hedgehog, since then having sold over 80 million copies across all games by 2011. Artist Naoto Ohshima, designer Hirokazu Yasuhara and programmer Yuji Naka are generally credited with the creation of the character.
Sonic hedgehog is a secreted protein that in humans is encoded by the SHH gene. It is the best studied ligand of the hedgehog signaling pathway, others being desert hedgehog (DHH) and Indian hedgehog (IHH). It plays a key role in the development of animals, from insects to mammals.
Why is Sonic the Hedgehog so popular?
As a result of this popularity, he has been referred to in various parts of culture. One of a class of genes involved in fruit fly embryonic development, called hedgehog genes, has been named “sonic hedgehog” after the character. Sonic has sometimes appeared in relation to various sports teams Sega have sponsored.
What is the sonic hedgehog pathway (Shh)?
It is already known that Sonic hedgehog (Shh) pathway is important for the evolution of radio and chemo-resistance of several types of tumors. Most of the brain tumors are resistant to chemotherapeutic drugs, consequently, they have a poor prognosis.